Objective: To probe into the problems of anti-infection treatment for neonates in Hunan Children’s Hospital and summarize the experience and effect of anti-infection consultations for neonates by clinical pharmacists. Methods: From May 2019 to May 2020

310 anti-infection consultations in neonatology participated by clinical pharmacists in our hospital were statistically analyzed. Results: From May 2019 to May 2020

clinical pharmacists participated into 310 anti-infection consultations in neonatology. The top three consultation purposes were 174 cases (54.89%) of poor initial therapeutic efficacy requiring adjustment of regimen

37 cases (11.67%) of assistance in identifying contaminated

colonized or pathogenic bacteria (whether anti-infection treatment was needed or not) and 36 cases (11.36%) of antifungal drug selection. The top three consultation opinions given by clinical pharmacists were 183 cases (57.73%) of adjustment of antibacterial drug administration regimen

71 cases (22.40%) of continuation or optimization of original drug administration regimen

and 37 cases (11.67%) of comprehensive evaluation on use of antibacterial drugs combined with clinical practice. The consultation opinion was adopted by 273 cases (88.06%) clinically. The disease turned out to be effective in 237 cases

with an effective rate of 86.81% (237/273). Conclusion: Clinical pharmacists provide pharmaceutical care for clinicians and children through participating into the clinical consultations

which plays a positive role in promoting diagnosis and treatment of diseases and rational drug use in children

as there is some confusion among clinicians in neonatal anti-infection treatment.